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Men with lifelong premature ejaculation also have specific imbalances in neurotransmitter function, and increased sensitivity to vibration in the pelvic area.Modern clinical treatment has moved from a psychological to a biochemical approach Système Délivrance using medication. Unfortunately, till recently, drugs used to manage rapid ejaculation needed to be taken over a period of time and caused other negative sexual side effects.The newly available medication dapoxetine (approved in some countries but not yet the US) is a short-acting version of older treatments, and reduces many of these problems. It typically delays ejaculation by about 300% if taken one hour before sex.

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While effective, dapoxetine is expensive, may cause nausea and there is little research on the long term health effects of using it regularly. Other pharmacological treatments are being investigated.And although they are not widely publicized, there are a number of off-the-shelf herbal and nutritional supplement products that can fairly reliably delay ejaculation.Researchers have recently proposed using a dual approach in recognition of the fact that using a medication-only approach is always a temporary solution.The new approach to manage PE effectively is to combine a short-term "medication-based" approach to allow the user to develop confidence and give enjoy sex during experimentation and personal practice, along with a long-term approach of sensate and techniques training to reduce over-rapid arousal.